Acinic cell carcinoma is also known as serous cell carcinoma or adenocarcinoma. It is a malignant epithelial neoplasm in which neoplastic cells express acinar cell differentiation.
Acinic cell carcinoma tends to be encapsulated and lobulated and mostly affects parotid salivary gland. Inside the oral cavity it mostly affects lips and buccal mucosa. It affects middle age people more with a predilection towards females.
Microscopically it contains cells that are positive to periodic acid Schiff (PAS) staining.
Treatment generally includes the surgical excision of tumor saving the facial nerve unless it is involved. Lymph nodes may also be dissected in case of clinical involvement.Prognosis may be poor in case of association with pain or fixation or gross invasion.
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